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Meet the Team

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Manideep Chavali

Principal Investigator

Manideep is an Assistant Professor in the Department of Pediatrics and Papé Family Pediatric Research Institute at Oregon Health & Science University (OHSU). He received his PhD from Stony Brook University in 2016 and completed his postdoctoral training at the University of California, San Francisco, in the laboratory of Dr. David Rowitch. His research focuses on how neurovascular and metabolic interactions regulate myelination and white matter repair, and how disruption of these processes contributes to neurological disease. His work is supported by the NIH, American Heart Association, Children's Heart Foundation, Cerebral Palsy Alliance Research Foundation, and Race to Erase MS Foundation.

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Thaddeus Kunkel

Postdoctoral Fellow

Thad graduated from Michigan State University with a Bachelor of Science in Neuroscience in 2016 and from the University of Michigan with a PhD in Molecular and Pathology in 2023. At the University of Michigan, Thad worked under the mentorship of Dr. Andrew Lieberman, studying oligodendrocyte dysfunction in Niemann-Pick Disease Type C, a rare lysosomal storage disease. He found that proper cholesterol homeostasis is necessary for epigenetic regulation of oligodendrocyte differentiation and function. Thad is interested in continuing to study how glial cells behave during development and the role these cells play in disease pathogenesis. Outside of the lab, Thad enjoys hiking, camping, fishing, cooking, baking, gardening, and eating new foods - preferably with his partner and cat by his side.

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Isa Maxwell

Graduate Student (NGP)

Isa received his B.A. in Biology from Lewis and Clark College in 2017, where he used Drosophila to study neuromuscular junction development. He joined the lab of Dr. Marc Freeman at OHSU after completing the Neuroscience PREP program, studying the role of astrocytes in neuronal circuit signaling. As a graduate student he studies the interplay of vasculature and oligodendrocyte precursor cells in the Chavali lab.

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Kat Gemperli 

Graduate Student (NGP)

Kat graduated from Washington University in St. Louis in 2021 with a B.A. in Neuroscience. After completing their degree, Kat worked in the Aravamuthan Lab where they helped develop a novel mouse model of preterm birth to study parvalbumin interneuron pathology underlying dystonia in cerebral palsy. Through this project, Kat became interested in how glia may impact neurodevelopment. This led them to join the Popko Lab at Northwestern University where they characterized myelin deficits induced by vascular stress in mice. As the newest graduate student in the Chavali Lab, Kat is studying glial cell energy metabolism in neurodevelopmental and disease contexts. In their spare time, Kat enjoys backpacking, roller skating, making art, and spending time with their cat.

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Beck Wise

Research Assistant

Beck graduated from Linfield University in 2024 with a B.A. in Biochemistry and Molecular Biology. Through the Murdock Program at OHSU, she interned at the Knight Cancer Research Institute and researched RUNX1-FPD associated Acute Myeloid Leukemia. Prior to joining the Chavali Lab, Beck worked at the Oregon National Primate Research Center in the Infectious Disease Resource. Her research interests include the biology of development and disease. Outside of the lab, Beck’s hobbies include pottery and hiking.

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Iris Farnum 

Research Assistant 

Iris graduated from Eckerd College in 2023 with a Bachelors of Science in Biology and Spanish.  At Eckerd, Iris worked in the lab of Dr. Denise Flaherty researching the molecular and cellular pathology of Alzheimer’s and Parkinson’s Disease. Iris spent a summer at Massachusetts General Hospital’s Center for Genomic Medicine in the lab of Dr. James Gusella studying Huntington’s Disease. Her research interests include developmental biology and the cellular pathology of neurodegenerative diseases. Outside of the lab, Iris enjoys reading, swimming, and running.

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Joshua Page

Research Assistant

Joshua Page is currently a Research Assistant II in the Chavali lab at OHSU. He graduated from Portland State University with a Bachelors of Science in Biology and Biochemistry. He is interested in all areas of biology, but especially in the application of genetics to explore the biology of development, and of disease. Joshua enjoys working with animals, and learning new experimental techniques. His favorite parts of working as a biologist are the moments when he learns something new about how the natural world works. His hobbies include reading, backpacking, and hiking. He also likes writing software in his spare time.

Past Members

Oregon Health & Science University, Papé Family Pediatric Research Institute, Lamfrom Biomedical Research Building-353,

3181 SW Sam Jackson Park Rd, Portland, OR 97239

chavali@ohsu.edu

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